Excellence in Fluorinated Pharmaceutical Intermediates – Baokai Pharma Sets the Benchmark in High-End Fluorochemicals

Located in the Qidong Life and Health Industrial Park, Jiangsu Province, a technology-driven enterprise that has been dedicated to the field of fluorinated fine chemicals for nearly two decades—Nantong Baokai Pharmaceutical Co., Ltd.—is steadily advancing in the specialized niche of fluorinated pharmaceutical intermediates with its formidable technical capabilities and well-established industrial footprint, emerging as one of the leading forces in this sector in China.

Corporate Profile: Founded in 2006, Deeply Rooted in Fluorinated Pharmaceuticals

Nantong Baokai Pharmaceutical Co., Ltd. was established in 2006, originally operating as Nantong Baokai Chemical Co., Ltd. before officially adopting its current name in 2019. Located in the Qidong Life and Health Industrial Park, Jiangsu Province, the company occupies 46 mu (approximately 3.07 hectares) with a registered capital of 25 million RMB. It is a national high-tech enterprise integrating scientific research, development, production, and sales.

The company has built an "industry-academia-research integrated" R&D system, establishing long-term and close collaborative relationships with renowned domestic and international universities, including Zhejiang University, Zhejiang University of Science and Technology, and the University of Emden-Leer in Germany. All of its products are backed by independent intellectual property rights. The company has obtained ISO 9001 Quality Management System, ISO 14000 Environmental Management System, and ISO 45001 Occupational Health and Safety Management System certifications, and has passed the provincial safety standardization compliance assessment. In recent years, the company has been honored with multiple awards, including "National High-Tech Enterprise," "Jiangsu Provincial Specialized and Sophisticated SME," "Jiangsu Provincial Service-Oriented Manufacturing Demonstration Enterprise," and "Qidong Top 100 Industrial Enterprise."

Star Products: A Professional Matrix of Fluorinated Intermediates, Three Series Covering Key Pharmaceutical Stages

Baokai Pharmaceutical's core competitive advantage lies in the R&D and production of fluorinated fine chemicals. The company has successfully developed and commercially manufactured three major series of fluorinated pharmaceutical intermediate products:

• Trifluoroacetic Acid Series: Including trifluoroacetic acid, trifluoroacetic anhydride, ethyl trifluoroacetate, methyl trifluoroacetate, and others. These are key raw materials for fluorinated drug synthesis and are widely used in the pharmaceutical and agrochemical sectors.

• Difluoroacetic Acid Series: Including difluoroethanol, ethyl difluoroacetate, and others. As important pharmaceutical intermediates, they play an irreplaceable role in the synthesis of antiviral and antibacterial drugs.

• Chlorodifluoroacetic Acid and Bromodifluoroacetic Acid Series: Including chlorodifluoroacetic acid, ethyl chlorodifluoroacetate, sodium chlorodifluoroacetate, ethyl bromodifluoroacetate, and others. This comprehensive product line meets diverse customer requirements.

In addition, the company is actively advancing the construction of its "200 t/year Celecoxib API and 3,000 t/year lithium battery electrolyte project," leveraging its fluorochemical expertise to expand into integrated API-to-formulation development and the new energy materials sector.

Industry Advantages: A Leader in a Specialized Niche, Driven by Both Technology and Services

1. Prominent Position in the Specialized Segment

In the specialized field of trifluorinated derivatives, Nantong Baokai Pharmaceutical ranks among the industry leaders, holding the fourth position nationally, with products and technologies at the forefront of the sector. With nearly two decades of deep cultivation in fluorinated fine chemicals for pharmaceutical applications, the company has built substantial technological barriers and a rich client network.

2. Advanced Core Technology and Processes

The company employs an indirect fluorination process to introduce the trifluoromethyl group, a technology notable for its readily available raw materials, mild reaction conditions, high selectivity, and excellent yields. As of 2025, the company holds 64 patents, reflecting its continuously strengthening technological innovation capabilities.

3. Outstanding Customized Service Capabilities

The company has established a product customization service platform, enabling deep engagement in clients' R&D projects. It offers nearly one hundred types of fluorinated pharmaceutical intermediate products and technical services, delivering full-lifecycle customized solutions from order receipt, design and development, production, and logistics to after-sales support. This service model has enabled the company to forge long-term, stable business relationships with numerous world-renowned enterprises.

4. Comprehensive International Certifications and Green Compliance

The company has obtained triple certifications—ISO 9001:2015 Quality Management System, ISO 14000:2015 Environmental Management System, and ISO 45001:2018 Occupational Health and Safety Management System—and has passed the provincial safety standardization compliance assessment. Product compliance fully meets the requirements of both domestic and international clients.

Development Vision

Looking ahead, Nantong Baokai Pharmaceutical Co., Ltd. will continue to deepen its presence in the fluorinated fine chemicals sector. Leveraging its existing technological accumulation and industry-academia-research collaborative advantages, the company will accelerate the construction of its new Celecoxib API and lithium battery electrolyte projects, further expanding its integrated API-to-formulation business layout. Committed to its production philosophy of "Technological Innovation, Environmental Friendliness, Energy Efficiency, and Quality First," and guided by its corporate spirit of "Integrity and Pragmatism, Enterprise and Progress, Win-Win Cooperation, and Pursuit of Excellence," Baokai Pharmaceutical is steadily advancing toward its goal of becoming a world-class enterprise in the field of fluorinated pharmaceutical intermediates, working hand in hand with global partners to create a brighter future together.

Enterprise Contact Information

Address: No.68 Suzhou road, Binjiang Fine Chemical Industrial Park, Beixin town Qidong City, Jiangsu, China

ChemNet Shop: www.chemnet.com/ChinaSuppliers/33629/

Tel: +86-513-83886111;+86-15068135816

Email: sales@baokaichem.com