Dual-Base Synergy: Best Chemical and Baoshengde Forge a High Ground in the Acyl Chloride and Silane Industry

From Nantong in Jiangsu Province along the Yangtze River to Zhijiang in Hubei Province at the gateway to the Three Gorges, a company with over two decades of deep roots in the fine chemical sector is writing a new chapter of leapfrog development through its "dual-base" model. Nantong Best Fine Chemical Co., Ltd. and Hubei Baoshengde Pharmaceutical Co., Ltd. —the former serving as the birthplace and R&D technology center, and the latter as the capacity-expansion and intelligent manufacturing base—together form a formidable industrial high ground for acyl chloride and silane fine chemical products.

Accumulated Strength, Building Dual-Base Synergistic Advantages

Nantong Best Fine Chemical Co., Ltd. was established in 2000. Located in the Sunchang Industrial Park of Haimen, it faces Shanghai across the river and enjoys convenient transportation. The company covers an area of 27,062.85 square meters, employs 200 staff (including 37 technical personnel), and has fixed assets exceeding 52 million yuan. Recognized as a "National High-Tech Enterprise" and a "Provincial Private Science and Technology Enterprise" by Jiangsu Province, Best Chemical has accumulated profound technical expertise in the R&D and production of acyl chlorides and silanes.

To expand production capacity and achieve intelligent upgrades, the company was introduced as a key investment project in 2019 to the Yaogang Chemical Industrial Park in Zhijiang, Hubei, where it established Hubei Baoshengde Pharmaceutical Co., Ltd. With a total investment of 500 million yuan and covering 150 mu (approx. 10 hectares), this facility commenced production in 2022. This strategic move established the dual-drive structure of "Nantong R&D + Zhijiang Smart Manufacturing." Leveraging the comprehensive industrial chain support of the Yaogang Chemical Industrial Park, including proximity to raw materials like chlorine gas, Baoshengde Pharmaceutical has achieved efficient and synergistic production.

With over two decades of deep industry experience, the company has been recognized as a National High-Tech Enterprise, a Jiangsu Provincial Private Science and Technology Enterprise, a Provincial Specialized and Sophisticated "Little Giant" SME, and a Provincial Gazelle Enterprise. It has also been rated as a Nantong AAA-Level Contract-Abiding and Creditworthy Unit. The company holds ISO9001 and ISO14001 dual-system certifications. Key products including oxalyl chloride, tert-butyldimethylchlorosilane, and triethylsilane have been designated as Provincial High-Tech Products. Holding multiple independent synthesis invention patents and possessing complete qualifications for hazardous chemical production and import/export, the company exports extensively to Europe, the Americas, and Southeast Asia. It is a long-term supplier to leading domestic and international pharmaceutical and agrochemical companies such as Pfizer, Johnson & Johnson, Syngenta, and HEC Pharma.

Flagship Products Lead, Focusing on High-Value-Added Segments

The company's core product lines are highly concentrated in two major areas: acyl chlorides and silanes, covering high-end intermediates for pharmaceuticals, pesticides, and new materials. The three flagship products collectively hold over 60% of the domestic market share.

• Flagship Products: Oxalyl Chloride and tert-Butyldimethylchlorosilane (TBSCl) are the company's two signature products. Additionally, products like Oxalyl Chloride Monomethyl Ester, Oxalyl Chloride Monoethyl Ester, and Triethylsilane have all been recognized as "High-Tech Products" by the Jiangsu Provincial Department of Science and Technology, with independent intellectual property rights.

• Key Applications: These products are critical intermediates for synthesizing high-end chemicals, including pharmaceuticals (e.g., the antiviral drug Oseltamivir), pesticides, and coatings. For instance, triethylsilane is a vital raw material for oseltamivir synthesis, while oxalyl chloride is used in the production of plant growth regulators and antibiotics.

1. Acyl Chloride Series (Core Advantage Category)
   

   Products include Oxalyl Chloride, Oxalyl Chloride Monomethyl Ester, Oxalyl Chloride Monoethyl Ester, and Phosphorus Oxychloride. With stable purity≥99% and strictly controlled impurity levels, they are widely used in the synthesis of antibiotics, cardiovascular drugs, and agrochemical intermediates like herbicides. The company maintains sufficient inventory for bulk drum supply.

2. Silane Protecting Agent Series
   

   This series includes tert-Butyldimethylchlorosilane (TBSCl), tert-Butyldiphenylchlorosilane, Triethylsilane, Triethylchlorosilane, Triisopropylsilane, and tert-Butyl Chloride. These serve as critical hydroxyl-protecting reagents in the synthesis of novel peptide and nucleoside drugs. The company boasts mature processes and leading yields, catering to both innovative drug R&D and commercial production needs.

3. Custom Fine Chemicals
   

   Leveraging its in-house R&D laboratories, the company undertakes custom synthesis projects. It can develop novel acyl chlorides and silane derivatives according to client specifications, offering one-stop services from gram-scale samples to thousand-ton commercial production.

Technology Leadership, Smart Manufacturing Driving the Future

The company's industry advantages are rooted in continuous technological innovation and intelligent transformation. At Baoshengde Pharmaceutical, over 10 million yuan has been invested in technological upgrades to automate production processes and create a "smart factory" environment. Post-upgrade, each workshop requires only a few workers for routine inspections, significantly enhancing production efficiency and intrinsic safety levels. In 2025, the company's annual output of high-end pharmaceutical chemicals surpassed 2,000 tons, generating an annual output value of 250 million yuan.

With its robust technological capabilities, advanced processes, and strict quality and environmental management systems (ISO9001 and ISO14001 certified), the company has earned the honor of "AAA-Level Contract-Abiding and Creditworthy Enterprise." It provides high-quality, compliant custom intermediate services to renowned domestic and international pharmaceutical companies.

Looking ahead, the company will continue to uphold its philosophy of "Customer First, Quality Foremost." Leveraging the synergistic advantages of its Nantong and Zhijiang bases, it aims to deepen its leading position in specialized niche segments and steadily advance towards its vision of "becoming a world-class chemical manufacturer."

Enterprise Contact Information

Address: Yaojiagang Chemical Industry Park, Zhijiang City, Yichang City, Hubei Province, China (Hubei Boashengde)

ChemNet Shop: www.chemnet.com/ChinaSuppliers/15592/

Tel: +86-513-82606266,82606506(Switchboard);+86-13951004954

Email: bsd@bsdxu.com