Lianyungang Huayijia: A Technology Leader in Amines and Acids

Located within the provincial-level chemical industrial park–the Lingang Industrial Zone in Guanyun County, Lianyungang, Jiangsu Province–Lianyungang Huayijia Chemical Co., Ltd. is steadily advancing with solid technical expertise and a comprehensive product portfolio. The company, formerly known as Changzhou Rundei Chemical Co., Ltd., is now situated east of Jingqi Road and north of Weiwu Road in the Lingang Industrial Zone, covering an area of approximately 20,001 square meters. Since its establishment in 2008, the company has been consistently dedicated to the development and production of pharmaceutical intermediates and fine chemicals.

Industry-Academia-Research Collaboration: Building a Technological Stronghold

Huayijia Chemical deeply recognizes that technological innovation is the core driving force for enterprise growth. Over the years, the company has maintained close collaborative relationships with renowned universities and research institutions, including Sichuan University, China Pharmaceutical University, and the Sichuan Antibiotics Research Institute, committing itself to the R&D of high-value-added, high-tech-content products. In core fine chemical process areas such as hydrogenation reduction, amination, alcoholization, and cis-trans isomer separation, the company has accumulated extensive production experience, with some product technologies reaching domestically leading levels. This integrated "industry-academia-research" development model provides a solid technological foundation for the company's consistent output of high-quality products.

A Rich Product Portfolio: Building Core Competitiveness

Leveraging its strong R&D capabilities and sophisticated production processes, Huayijia Chemical has established a product system encompassing five major categories and over 30 products, with amines and acids at its core. Its main products include key pharmaceutical intermediates such as 1-methyl-3-phenylpropylamine, dibenzosuberone (DBS), and 3-hydroxypiperidine. In addition, the company offers dozens of other fine chemical products, including 4-methoxyphenethylamine, isopropylbenzylamine, p-methoxyphenylacetonitrile, 3,4-dimethoxycinnamic acid, 2,3-dichlorobenzyl cyanide, and traxoprodil, fully demonstrating its deep expertise and extensive footprint in the field of organic synthesis.

The following five key products are among the company's best-selling items:

1. N-(2,3-Dimethoxybenzyl)piperonylamine Hydrochloride

CAS: 430433-40-2 | Molecular Formula: C₁₉H₂₃NO₄·HCl | Appearance: White to off-white crystalline powder

This product is a critical intermediate for berberine (the active ingredient in the traditional remedy Huangliansu) synthesis and impurity analysis. Its molecular structure contains both dimethoxybenzyl and piperonylamine moieties, giving it significant importance in pharmaceutical synthesis. Leveraging its technical expertise in amination reactions, Huayijia Chemical can supply high-purity products that meet the stringent requirements of pharmaceutical companies for impurity reference standards and synthetic raw materials.

2. 2,3-Dimethoxybenzaldehyde (o-Veratraldehyde)

CAS: 86-51-1 | Molecular Formula: C₉H₁₀O₃| Appearance: Colorless or white needle-like crystals

This product serves as a core pharmaceutical intermediate in the synthesis of berberine. Together with the aforementioned product, it provides a synergistic and comprehensive intermediate solution for downstream berberine manufacturers.

3. Azetidine-3-carboxylic Acid

CAS: 36476-78-5 | Molecular Formula: C₄H₇NO₂| Appearance: White solid or light yellow powder

This product is a four-membered nitrogen heterocyclic compound that serves as an important building block in pharmaceutical and agrochemical research. It has broad application value in peptide synthesis and the construction of drug molecular frameworks.

4. 3-Hydroxyazetidine Hydrochloride

CAS: 18621-18-6 | Molecular Formula: C₃H₇NO·HCl | Appearance: White to off-white crystalline powder

The core value of this product lies in its role as a key intermediate for the active pharmaceutical ingredient Baricitinib. Baricitinib is a JAK inhibitor used for the treatment of moderate to severe active rheumatoid arthritis. Huayijia Chemical's production capability for this high-value-added intermediate reflects its strategic depth in the field of high-end pharmaceutical intermediates.

5. trans-1,4-Cyclohexanediamine

CAS: 2615-25-0 | Molecular Formula: C₆H₁₄N₂| Appearance: White to off-white crystalline solid

This product has diverse applications: it serves as a raw material for polymer materials in the synthesis of polyamides and polyurethanes; it is used as a ligand or ligand precursor in the pharmaceutical field; and it can also act as a metal coordination reagent in catalysis and other areas. Huayijia Chemical's expertise in cis-trans isomer separation ensures efficient access to the trans-isomer product with excellent purity.

Integrity as the Foundation: Creating a Shared Future

Over more than a decade since its establishment, Lianyungang Huayijia Chemical Co., Ltd. has consistently adhered to the business philosophy of "science and technology as the guide, quality as the lifeblood." The company is committed to building a technology-driven chemical manufacturer with robust capabilities in high-tech product development, a distinctive product portfolio, reliable product quality, a highly qualified workforce, and a sound management system. Huayijia Chemical looks forward to engaging in extensive cooperation with partners from both domestic and international markets, jointly driving the progress and development of the pharmaceutical and chemical industry.

Enterprise Contact Information

Address: Weiwu Road,Industrial Park,Yanwei Port,Guanyun County,Lianyungang City, Jiangsu Province, China

ChemNet Shop: www.chemnet.com/ChinaSuppliers/24268/

Tel: +86-518-88581610;+86-13806140155

Email: joysan@jt-greenchem.com